Table 3.
Univariable (left – Model 1) and multivariable (right – Model 3) logistic regression analyses demonstrating prognostic significance of CITV point groupings for one-year survival in comparison to ds-GPA (middle – Model 2)
| MODEL 1 – CITV alone | MODEL 2 – ds-GPA | MODEL 3 – ds-GPA-CITV | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | Statistical Significance | Hazard Ratio | Statistical Significance | Hazard Ratio | Statistical Significance | |
| CITV (per point grouping increase) | 0.314 | P=.007 | – | – | 0.256 | P=.042 |
| KPS (per point grouping increase) | – | – | 1.659 | P<.001 | 1.620 | P<.001 |
| Number of metastases (per point grouping increase) | – | – | 0.456 | P=.002 | 0.451 | P=.003 |
| Akaike Information Criteria | 382 | 380 | ||||
CITV = Cumulative Intracranial Tumor Volume; ds-GPA = disease-specific graded prognostic assessment; KPS = Karnofsky Performance Score.