Table 5.
Demographic and tumor profile in left- vs right-sided primary tumors
| Left-sided (splenic flexure and distal) N = 642 |
Right-sided (transverse colon and proximal) N = 158 |
p value | |
|---|---|---|---|
| Age, mean (range) | 46.5 yrs (15–85 yrs) | 50.1 yrs (11–82 yrs) | 0.006 |
| Male gender | 420 (65.4%) | 97 (61.4%) | 0.343 |
| Mean CEA (ng/mL) (range) | 296.1 (0.49–62,952) | 106.7 (0.47–4806) | |
| Median CEA (ng/mL) | 5.97 | 5.6 | |
| Histology | |||
| Signet ring | 79 (12.3%) | 28 (17.7%) | 0.073 |
| Mucinous | 101 (15.7%) | 32 (20.25%) | 0.172 |
| Stage IV disease | 174 (27.1%) | 56 (35.4%) | 0.029 |
| Site of metastasis | |||
| Liver | 91 (14.1%) | 24 (15.1%) | 0.252 |
| Lung | 56 (8.7%) | 8 (5.0%) | 0.011 |
| Peritoneal | 48 (7.5%) | 29 (18.3%) | 0.001 |
| Ovariana | 8 (3.6%) | 7 (11.5%) | 0.015 |
| Bone | 10 (1.5%) | 1 (<1%) | 0.232 |
aIn women with CRC