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. 2017 Nov 24;5:250. doi: 10.3389/fped.2017.00250

Table 1.

Pooled analysis.

Total patients 373 children
Sex 254F (68.1%) 119 M (31.9%)
Mean age 9.98 years (range, 3–18 years)
Teratoma or malignancy present 66 (17.6%)
CSF positive for anti-NMDAR 327 (87.6%)
Serum positive for anti-NMDAR 276 (74%)
First-line treatments
High-dose corticosteroids 335 (89.8%)
Intravenous immunoglobulin 296 (79.3%)
Plasma exchange 116 (31%)
Second-line treatments
Rituximab 87 (23.3%)
Cyclophosphamide 62 (16.6%)
Third-line treatments
Electroconvulsive therapy 5 (1.3%)
Mechanical ventilation 14 (3.8%)
Outcomes
Complete recovery with minor deficits 187 (50.1%)
Partial recovery with major deficits 174 (46.7%)
Death 12 (3.2%)