Table 1.
Reporter expression in cell populations from naïve lung digest and peripheral blood.
| Csf1r-Cre | LysM-Cre | CX3CR1-ERCre | CD68-rtTA | ||
|---|---|---|---|---|---|
| Lung digest | ResAM | 98.3 ± 0.4 | 96.1 ± 1.8 | ≤1 | 2.59 ± 0.8 |
| IM1 | 99.8 ± 0.3 | 98.5 ± 0.8 | 86.6 ± 1.5 | 76.13 ± 3 | |
| IM2 | 99.6 ± 0.5 | 98.9 ± 0.8 | 95.7 ± 5 | 80 ± 4.3 | |
| IM3 | 99.8 ± 0.1 | 93.7 ± 1.9 | 88.1 ± 2.5 | 72.5 ± 7.2 | |
| CD11b+ DC | 99.6 ± 0.4 | 52.8 ± 3.8 | 81.6 ± 7.5 | 71.6 ± 7.3 | |
| CD103+ DC | 99.7 ± 0.3 | 44.8 ± 5.5 | 12.5 ± 6.4 | 73.8 ± 6.8 | |
| T cells | 95.6 ± 6.5 | 5.2 ± 1.5 | 3.3 ± 3.2 | 5.1 ± 1.8 | |
| B cells | 79 ± 9.5 | 5.4 ± 1 | ≤1 | 7.4 ± 1 | |
| γδ T cells | 95.1 ± 5.2 | 3.1 ± 0.74 | 5.4 ± 1.5 | 2.8 ± 0.8 | |
| NK cells | 98.9 ± 1.8 | 15.6 ± 2.5 | 40.1 ± 15.2 | 10.2 ± 1.3 | |
| Endothelial cells | ≤1 | ≤1 | ≤1 | ≤1 | |
| Epithelial cells | ≤1 | 22.3 ± 7.3 | ≤1 | ≤1 | |
| Blood | Neutrophils | 99.5 ± 0.4 | 98 ± 1.1 | 1.7 ± 1.4 | 58.7 ± 9.7 |
| Eosinophils | 93 ± 5.1 | 19.8 ± 1.6 | ≤1 | 1.2 ± 0.5 | |
| Ly6Chi monocytes | 100 ± 0 | 67 ± 4.9 | 51 ± 4.8 | 70.5 ± 6.3 | |
| Ly6Clo monocytes | 99.9 ± 0.9 | 86.5 ± 1.4 | 91.5 ± 9.1 | 63.8 ± 4.3 | |
| T cells | 98.5 ± 1 | 6.7 ± 1.8 | 6.9 ± 3.3 | 6.9 ± 2.2 | |
| B cells | 82.5 ± 3.5 | 6.1 ± 0.9 | ≤1 | 8.3 ± 2.7 | |
Data are presented as mean ± SD, n = 3–5 mice per group.