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. 2017 Nov 28;7:16494. doi: 10.1038/s41598-017-16392-4

Figure 5.

Figure 5

Determination of C-Cpl-7 configuration in solution by SAXS. (a) Overlay of the scattering curve of C-Cpl-7 wt at infinite dilution (black dots) with the scattering profile calculated from the full-length domain crystal structure using CRYSOL and the fit obtained by rigid-body modelling (BUNCH) (orange and grey traces, respectively). The inset shows the real-space distance-distribution functions P(r) for the configuration in solution (black trace) and the crystal structure (orange trace). (b) Ab initio bead model of C-Cpl-7 reconstructed from SAXS data using DAMMIF. (c) Superposition of the DAMMIF model in mesh representation with the best rigid model (cartoon) produced by BUNCH.