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. 2017 Nov 24;8:877. doi: 10.3389/fphar.2017.00877

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Copyright © 2017 Dou, Shen, Tao, Huang, Shi, Chen, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-130 abolished the anti-proliferation effect of curcumin by downregulating nkd2. (A) RT-q-PCR of the mRNA level of Nkd2 in SW480 cells with the treatments as indicated. Data were represented as mean ± SD; n = 3 independent experiments. ^∗p < 0.05, ^∗∗∗p < 0.001. (B) RT-q-PCR of the mRNA level of LPR6 in SW480 cells with the treatments as indicated. Data were represented as mean ± SD; n = 3 independent experiments. (C) Western blot analysis of the protein level of NKD2 and LPR6 in SW480 cells with the treatment as indicated. n = 3 independent experiments and this panel presented one of these repeats.