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miR-130a showed higher level in the short-lived mice treated with curcumin. Mice treated with curcumin in Figure 1A (n = 20) was divided into two groups. Short-lived group indicated the mice lived less than 100 days (n = 13) while long-lived group indicated the mice lived more than 100 days (n = 7). Q-PCR showed the expression level of miRNAs in the serum of each mice. ∗p < 0.05.
