Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 28;7:16495. doi: 10.1038/s41598-017-16472-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Overlap of up- and down-regulated pathways among KEGG, GSEA and PPI. (a) A total of 3 up-regulated pathways were overlapped in the KEGG, GSEA and PPI: the SLE, cell cycle and DNA replication pathways. (b) A total of 7 down-regulated pathways were overlapped between KEGG, GSEA and/or PPI, including pathways involved in calcium signaling, focal adhesion, cell adhesion molecular, etc. (c) The GSEA results of the three pathways are shown, demonstrating that the DNA replication, cell cycle and SLE pathways were significantly increased, with an NES of 3.10, 3.00 and 2.39, respectively, in cervical squamous cell cancer patients. (d) The GSEA results of the top three pathways are shown, demonstrating that the vascular smooth muscle contraction, focal adhesion, and neuroactive ligand-receptor interaction pathways are significantly decreased, with an NES of −2.41, −2.02, −1.98, respectively, in cervical squamous cell cancer patients.