Table 3.
Proportional hazards model of time to cancer: hazard ratios of significant covariates
| Parameter | Label | HR (95% CI) | p Value |
|---|---|---|---|
| Age group | > 65 years | 3.04 (2.71–3.41) | < 0.0001 |
| DISTIME | Dx to index date | 1.08 (1.03–1.13) | 0.0020 |
| Corticosteroid | Corticosteroids any time | 1.35 (1.08–1.69) | 0.0088 |
| Sex | Female | 0.82 (0.74–0.90) | < 0.0001 |
| COPD | Yes | 1.59 (1.30–1.94) | < 0.0001 |
| Solid organ transplant | Yes | 2.72 (1.40–5.27) | 0.0031 |
| Charlson comorbidity index | > 1 Charlson score | 1.18 (1.04–1.33) | 0.0107 |
| Hypertension | Yes | 1.15 (1.02–1.30) | 0.0185 |
| Polypharmacy | > 5 medications | 1.22 (1.09–1.37) | 0.0006 |
CI confidence interval, COPD chronic obstructive pulmonary disease, DISTIME time from diagnosis to index date, Dx diagnosis, HR hazard ratio