Table 4.
Distribution of specific cancers among the elderly and younger age groups
| Cancera | Age 18–64 years [n = 52,578; 1717 events] | Age ≥ 65 years [n = 7338; 1093 events] |
|---|---|---|
| GI malignancies with an increased incidence in IBD | ||
| Colorectal cancer | 111 (6.5) | 43 (3.9) |
| Small bowel adenocarcinoma | 14 (0.8) | 5 (0.5) |
| Anal cancer | 5 (0.3) | 2 (0.2) |
| Cholangiocarcinoma | 8 (0.5) | 1 (0.1) |
| Cancers possibly related to IBD medications | ||
| Urinary tract malignancy | 83 (4.8) | 58 (5.3) |
| Melanoma | 94 (5.5) | 24 (2.2) |
| NMSC | 700 (40.8) | 529 (48.4) |
| Non-Hodgkin’s disease | 43 (2.5) | 22 (2.0) |
| Other cancers unrelated to IBD | ||
| Prostate cancer | 104 (6.1) | 100 (9.1) |
| Female breast cancer | 164 (9.6) | 77 (7.0) |
| Lung cancer | 32 (1.9) | 72 (6.6) |
| Pancreatic cancer | 17 (1.0) | 27 (2.5) |
| Acute myeloid leukemia | 7 (0.4) | 3 (0.3) |
| Othersb | 335 (19.5) | 130 (11.9) |
Data are expressed as number of events (%)
GI gastrointestinal, IBD inflammatory bowel disease, NMSC non-melanoma skin cancer
aPercentage of each cancer subtype in the first event of cancer, e.g. colorectal cancer made up 6.5% of all first cancer events in the younger group, and 3.9% in the elderly group, ordered from the highest incidence in the ≥ 65 years age group to the lowest
bAll other cancers, comprised of over 120 specific subtypes