Table 3. Distribution of APOE alleles and genotypes.
| Alleles/Genotypes | Controls (N=514) | All IS (N=513) | P value | OR (95%CI) |
|---|---|---|---|---|
| Alleles | ||||
| ε2 | 88(8.56) | 76(7.41) | 0.461 | 0.886(0.642–1.222) |
| ε3 | 866(84.24) | 842(82.07) | – | – |
| ε4 | 74(7.20) | 108(10.53) | 0.012 | 1.491(1.093–2.035) |
| Genotypes | ||||
| ε2/ε2 | 5(0.97) | 3(0.58) | 0.560 | 0.651(0.154–2.756) |
| ε2/ε3 | 70(13.62) | 63(12.28) | 0.765 | 0.945(0.652–1.370) |
| ε2/ε4 | 8(1.56) | 7(1.36) | 0.891 | 0.931(0.333–2.600) |
| ε3/ε3 | 366(71.21) | 347(67.64) | – | – |
| ε3/ε4 | 64(12.45) | 85(16.57) | 0.067 | 1.396(0.977–1.995) |
| ε4/ε4 | 1(0.19) | 8(1.56) | 0.045 | 8.449(1.050–67.999) |
| ε4 containing | 73(14.20) | 100(19.49) | 0.027 | 1.453(1.044–2.023) |