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. 2017 Nov 29;37(6):BSR20171092. doi: 10.1042/BSR20171092

Figure 2. Wnt5a increases clone formation, migration, and invasiveness of NSCLC cell in vitro.

Figure 2

(A) Wnt5a was knocked down in A549 cells, which was determined by the Western blotting. (B) siRNA-mediated silencing of Wnt5a profoundly reduced clone formation of A549 cells. (C) siRNA-mediated silencing of Wnt5a profoundly reduced migration and invasiveness of A549 cells. (D) Wnt5a was overexpressed in H1975 cells, which was determined by the Western blotting. (E) Overexpression of Wnt5a profoundly increased clone formation of A549 cells. (F) Overexpression of Wnt5a profoundly increased migration and invasiveness of A549 cells. A549 cells that transfected with the empty expression vector pcDNA6.2 and H1975 cells that transfected with the empty expression vector pcDNA3.1 were the corresponding controls. *P<0.05 compared with the control group.