Figure 5. The effects of Wnt5a knockdown on tumor volume, tumor weight, EMT-related proteins, and metastasis in vivo.
(A) The effect of Wnt5a knockdown on tumor volume at 0–28 days in A549 tumor-bearing mice. (B) The effect of Wnt5a knockdown on tumor weight at 28th day in A549 tumor-bearing mice. (C) The effect of Wnt5a knockdown on the expression levels of β-catenin, E-cadherin, N-cadherin, and vimentin in A549 tumor-bearing mice. (D) The effect of Wnt5a knockdown on NSCLC invasion and metastasis in vivo by pathological examination. *P<0.05 compared with the control group and * *P<0.01 compared with the control group.