FIG 2 .

Faecalibacterium colonization during late infancy is impacted by older siblings. (A) Heatmap of Spearman’s rank correlation coefficients between the relative abundance of Faecalibacterium and selected variables during late infancy in SKOT I, SKOT II, and ProbiComp. Statistical significance is indicated by asterisks as follows: **, P = 0.01; ***, P < 0.001. (B and C) Relative abundances (B) and prevalence of Faecalibacterium (C) in the combined data set (n = 482) during late infancy and toddlerhood stratified according to the number of older siblings. Mean values plus SD (error bars) are shown in panel B. Statistical significance is indicated by asterisks as follows: ****, P < 0.0001 by the Kruskal-Wallis test; ***, P < 0.001 by the chi-square test for trend.