B. Percentage of prescribed dose received (median values) in six plans by 2 cc rectum, sigmoid colon and urinary bladder in our study and commonly used HDR dose fractionations that will permit the same percentage dose to 2 cc OAR as shown in Table 4A

Applicator and optimization used	CTV	Rectum		Sigmoid colon		Urinary bladder
	D90 of CTV (as % of PD) in our study, when dose is normalized at point A	D2cc of rectum (as % of PD) in our study	Commonly used HDR dose fractionations that will allow this percentage dose to 2 cc rectum (see Table 4A, column e)	D2cc of sigmoid colon (as % of PD) in our study	Commonly used HDR dose fractionations that will allow this percentage dose to 2cc sigmoid colon (see Table 4A, column q)	D2cc of urinary bladder (as % of PD) in our study	Commonly used HDR dose fractionations that will allow this percentage dose to 2cc urinary bladder (see Table 4A, column cc)
FNO	145%	106.625%	None	44.5%	All	134.625%	None
RNO	89%	52.625%	All	34.6%	All	67.375%	All
FMO	123%	97.75%	None	42.6%	All	113.875%	None
RMO	80.75%	44.75%	All	25.8%	All	68.625%	All
FGO	100.8%	74.25%	f, g, i, o (from Table 4A, column e)	40.1%	All	115.125%	None
RGO	100.2%	59%	All	29.3%	All	75.875%	All

FNO – Fletcher style tandem ovoid applicator with no optimization, RNO – ring applicator with no optimization, FMO – Fletcher style tandem ovoid applicator with manual optimization, RMO – ring applicator with manual optimization, FGO – Fletcher style tandem ovoid applicator with graphical optimization, RGO – ring applicator with graphical optimization, PD – prescribed dose