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. Author manuscript; available in PMC: 2017 Nov 29.
Published in final edited form as: Gynecol Oncol. 2017 May 5;146(1):137–145. doi: 10.1016/j.ygyno.2017.04.008

Figure 3.

Figure 3

NanoString analysis of PBMCs identified 12 differentially expressed (p<0.05) immune genes amongst two time point comparisons. A. After the first cycle of chemotherapy 8 immune genes were differentially expressed versus 35 after the second cycle of chemotherapy. At the circle intersections are the 12 genes shared within two-group comparisons. B. The majority of genes were downregulated during chemotherapy as denoted by the arrow direction. C. Combined IPA analysis of the genes (panel B) identified the top canonical pathways in which these genes are involved. Only one, a natural killer pathway, was significant and included two genes involved in inhibition and one in activation.