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. 2017 Oct 25;9(11):337. doi: 10.3390/toxins9110337

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Box plots (min to max) showing IL-6 (left) and IL-8 (right) concentrations in cell culture supernatants of A549 (A), 16HBE14o- (B), hAECN (C) and hAECB (D) cells exposed for 24 h (16HBE14o-, hAECN and hAECB) or 48 h (A549) to single and combinational mixtures of DON, NIV and FX. Bar colors indicate the concentrations at which mycotoxins were used: white, light grey and dark grey for concentrations affecting the viability of 10%, 30% and 50% of cells, respectively. Data are from three independent experiments performed in triplicate. * Indicates statistically significant differences (p < 0.05) in cytokine levels between cells exposed and not exposed to mycotoxins.