Table 3.
Comparison of the five canonical pathways most significantly altered in bovine macrophage (BoMac) cells after 24 h of exposure to citrinin (CIT), ochratoxin A (OTA), or citrinin + ochratoxin A (CIT + OTA).
| Bio-Function-Associated Genes 1 | Number of Altered Genes |
|---|---|
| Citrinin | |
| Cell death and survival | 814 |
| Cellular movement | 520 |
| Lipid metabolism | 229 |
| Small molecule biochemistry | 397 |
| Cellular growth and proliferation | 846 |
| Ochratoxin A | |
| DNA replication, recombination and repair | 272 |
| Gene Expression | 97 |
| RNA post-transcriptional modification | 109 |
| Cellular development | 72 |
| Cell signaling | 85 |
| Citrinin + Ochratoxin A | |
| Cell cycle | 603 |
| Cellular growth and proliferation | 1368 |
| Gene expression | 858 |
| Post-translational modification | 539 |
| Cellular movement | 762 |
1 The five most significant functions for each treatment are listed.