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Partitioning-folding coupling of the P454-derived peptides. Helical content induced by the partition of peptides into POPC SUVs (A); DOPC SUVs (black squares) or DOPC/DOPG 8:2 SUVs (red circles) (B). For each peptide, the free energy of membrane partitioning is plotted as a function of the membrane-induced increase in helical content. Inset (B) Correlation between valence and membrane-induced helical content in the presence of DOPC/DOPG 8:2 SUVs. S.D. are ±0.1 kcal/mol.
