Table 1.
Clinical and Pathological Data at the Time of Resection of Primary Tumor
| Variable Demographical and Clinical Data (N=40) |
Recurrent Cases (n = 15) |
Non-Recurrent Cases (n = 25) |
P -Value |
|---|---|---|---|
| Age, Median (Min., Max.) | 71 (55, 83) | 74 (51, 80) | 0.726 |
| Sex, n (%) | 0.002 | ||
| Male | 9 (60%) | 21 (84%) | |
| Female | 6 (40%) | 4 (16%) | |
| Etiology, n (%) | 0.254 | ||
| HBV | 4 (26.66%) | 8 (32%) | |
| HCV | 7 (46.77%) | 5 (20%) | |
| None | 4 (26.66%) | 12 (48%) | |
| Fibrosis, n (%) | 0.083 | ||
| 0 | 0 (0%) | 4 (16%) | |
| 1-2 | 6 (40%) | 12 (48%) | |
| 3-4 | 9 (60%) | 9 (36%) | |
| Total bilirubin, mg/dl | 0.725 | ||
| Median (Min., Max) | 0.8 (0.6, 1.5) | 0.7 (0.5, 2.5) | |
| ≥ 1.0 | 1.3 (1, 1.5) | 1.2 (1.1, 2.5) | |
| INR | 0.026 | ||
| Median (Min., Max) | 1.09 (0.92, 2.43) | 1.02 (0.89, 1.29) | |
| ≥ 1.0 | 1.09 (1, 2.43) | 1.04 (1, 1.29) | |
| AFP, ng/ml | 0.791 | ||
| Median (SD) | 24.30 (2072) | 15.7 (2344) | |
| ≥ 20 | 102 (2703) | 914.8 (3671) | |
| Extent of resection, n (%) | 0.502 | ||
| Minor hepatectomy | 11 (73.33%) | 15 (60%) | |
| Major hepatectomy | 4 (26.67%) | 10 (40%) | |
| Tumor stage, n (%) | 0.543 | ||
| I-II | 11 (73.33%) | 17 (68%) | |
| III-IV | 4 (26.67%) | 8 (32%) | |
| Tumor size, n (%) | 0.730 | ||
| < 5 cm | 11 (73.33%) | 18 (72%) | |
| ≥ 5 cm | 4 (26.67%) | 7 (28%) | |
| Histological grade, n (%) | 0.686 | ||
| Well to moderate | 13 (86.67%) | 19 (76%) | |
| Poor | 2 (13.33%) | 6 (24%) | |
Min.: Minimum, Max.: Maximum, n/N: numbers, HBV: Hepatitis B Virus, HCV: Hepatitis C Virus, INR: International Normalised Ratio