Skip to main content
. 2017 Oct 23;8(19):4018–4026. doi: 10.7150/jca.21226

Figure 2.

Figure 2

CKAP4 was associated with ccRCC cell growth. A) Effective silencing of CKAP4 mRNA expression using 2 shRNAs; B) Effective upregulation of CKAP4 mRNA expression using CKAP4-bearing lentivirus; C) Protein level of CKAP4 corresponded to mRNA expression in response to shRNA downregulation and lentiviral upregulation; D) Upregulation of CKAP4 significantly increased proliferation and downregulation of CKAP4 significantly inhibited proliferation of both 786-O and RCC4 ccRCC cell lines; E) Upregulation of CKAP4 significantly increased cell invasion and migration, and downregulation of CKAP4 significantly inhibited cell invasion and migration of both 786-O and RCC4 ccRCC cell lines (**P < 0.01, n = 3, Lv = lentiviral).