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. 2017 Oct 23;8(19):4040–4047. doi: 10.7150/jca.21304

Figure 1.

Figure 1

Expression of the lncRNA GHRLOS in colorectal cancer. (A) The representative images of haematoxylin and eosin staining of cancer tissue and matched adjacent non-cancerous tissue from 2 CRC patients (original magnification, ×100). (B) The expression levels of GHRLOS were assessed by quantitative RT-PCR in cancer tissues and adjacent normal tissues from 366 patients. The expression levels of GHRLOS were normalized to the level of GAPDH. Note that the levels of GHRLOS in CRC tissues were significantly lower than those in adjacent non-cancerous tissues. ***, P < 0.001. (C) Relative GHRLOS expression (expressed as log2 fold change) in cancer tissues compared with matched non-cancerous tissues (n = 366). Patients with colorectal cancer were classified into either the decreased GHRLOS expression group (log2 fold change ≤ -1; n = 199) or the non-decreased GHRLOS expression group (log2 fold change > -1; n = 167) according to the changes in GHRLOS expression.