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. 2017 Oct 23;8(19):4040–4047. doi: 10.7150/jca.21304

Table 1.

GHRLOS expression and clinicopathological characteristics of patients with colorectal cancer

Characteristics Number of case GHRLOS expression P value
Decreased (n=199)
Number (%)
Non-decreased (n=167)
Number (%)
Age 0.465
> 65 years 159 83 76
≤ 65 years 207 116 91
Gender 0.253
Male 196 112 84
Female 170 87 83
Tumor site 0.930
Colon 135 73 62
Rectum 231 126 105
Tumor size 0.475
< 5 cm 214 113 101
≥ 5 cm 152 86 66
Histological subtype 0.281
Adenocarcinoma 341 188 153
Others 25 11 14
Histological grade 0.079
Well/Moderate 271 140 131
Poor 95 59 36
Depth of tumor invasion 0.074
T1+T2 110 52 58
T3+T4 256 147 109
Lymph node metastasis 0.033
Absence 217 108 109
Presence 149 91 58
Distant metastasis 0.005
Absence 315 162 153
Presence 51 37 14
Serum CEA level 0.136
≥ 10 ng/mL 268 152 116
< 10 ng/mL 98 47 51

CEA, carcinoembryonic antigen.