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The interactions between lncRNAs, miRNAs and mRNAs. A. There are several links between lncRNAs and miRNAs in GC: lncRNAs produce miRNAs through intracellular splicing; lncRNAs silence miRNAs by epigenetically mediation; lncRNAs regulate the expression of transcripts by combining competitively with miRNAs, called ceRNAs mechanism. B. MiRNAs affect post-transcriptional regulation by interacting with the 3ʹ-UTR of mRNAs. C. LncRNAs compete with mRNAs to combine with miRNAs.
