Table 2.
(a) Univariate and (b) multivariate analyses for the effects of GOLPH3 expression on the overall survival of 112 patients treated with radical cystectomy followed by standard GC chemotherapy for urothelial carcinoma of the bladder
Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|
Variable | HR | 95%CI | P | HR | 95%CI | P | ||
Gender | ||||||||
Male vs Female | 0.854 | 0.509-1.432 | 0.549 | 0.792 | 0.460-1.365 | 0.401 | ||
Age | ||||||||
>65 y vs ≤65 y | 1.186 | 0738-1.905 | 0.482 | 1.068 | 0.649-1.759 | 0.795 | ||
pT status | ||||||||
T3-T4 vs T2 | 1.637 | 1.004-2.671 | 0.048 | 1.843 | 1.063-3.196 | 0.030 | ||
Size | ||||||||
>3 cm vs ≤3 cm | 1.319 | 0.833-2.088 | 0.238 | 1.224 | 0.733-2.045 | 0.440 | ||
pN status | ||||||||
N1-N2 vs N0 | 1.654 | 1.019-2.686 | 0.042 | 2.360 | 1.386-4.019 | 0.002 | ||
Multiplicity | ||||||||
Multifocal vs Unifocal | 1.231 | 0.765-1.983 | 0.392 | 1.112 | 0.661-1.870 | 0.689 | ||
GOLPH3 expression | ||||||||
High vs Low | 1.805 | 1.122-2.902 | 0.015 | 1.808 | 1.085-3.013 | 0.023 |