Figure 10.
In vivo antitumor effect of YQ26-FSiNPs. (A) Schematic plan for the administration of PBS, Lib-FSiNPs, YQ26 or YQ26-FSiNPs. (B) Images of tumor. (C) Tumor volume. (D) Survival of tumor-bearing mice. Immunohistochemical imaging of tumor tissue sections after staining with (E) CD31, (F) Ki-67 and (G) TUNEL assay of apoptotic tumor cells; (H) Statistical analysis of blood vessel density by CD 31 antibody staining, (I) cell proliferation by Ki-67 antibody staining, (J) cell apoptosis by TUNEL. Values shown are mean ± SD; NS, not significant; *P < 0.05; **P < 0.01; ***P < 0.001.