Table 1.
Dose escalation plan.
| Dose level | Number treated | IP bortezomib (mg/m2) | IP carboplatin (AUC) |
|---|---|---|---|
| 1a | 6 | 0.5 | 5 |
| 1 | 6 | 0.5 | 4 |
| 2 | 5 | 0.9 | 4 |
| 3 | 3 | 1.3 | 4 |
| 4 | 3 | 1.7 | 4 |
| 5 | 3 | 2.1 | 4 |
| 6 | 6 | 2.5 | 4 |
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