Table 4.
Correlations among cytokines in POAG
| ρ/P value | BDNF | Cat D | sICAM-1 | MPO | sNCAM | sVCAM-1 | PAI-1 |
|---|---|---|---|---|---|---|---|
| BDNF | – | −0.103 | −0.402 | −0.192 | −0.378 | −0.412 | −0.455 |
| Cathepsin D | 0.631 | – | 0.432 | 0.072 | 0.369 | 0.592 | 0.290 |
| sICAM-1 | 0.052 | 0.035 | – | 0.425 | 0.743 | 0.737 | 0.751 |
| MPO | 0.368 | 0.740 | 0.038 | – | 0.312 | 0.269 | 0.551 |
| sNCAM | 0.069 | 0.076 | 0.000* | 0.138 | – | 0.603 | 0.775 |
| sVCAM-1 | 0.046 | 0.002* | 0.000* | 0.204 | 0.002* | – | 0.620 |
| PAI-1 | 0.025 | 0.169 | 0.000* | 0.005* | 0.000* | 0.001* | – |
POAG, primary open angle glaucoma; BDNF, brain-derived neurotrophic factor; Cat D,cathepsin D; sICAM, soluble intercellular adhesion molecule; MPO, myeloperoxidase; sNCAM, soluble neural cell adhesion molecule; sVCAM, soluble vascular cell adhesion molecule; PAI, plasminogen activator inhibitor
Correlation coefficient (ρ) and P values for each pair of cytokines are calculated by the Spearman’s correlation test
The P values are shown on the lower left side and ρ on the upper right side of the table
*Significance level at 5% (P < 0.0083), by Bonferroni correction for multiple comparisons