Fig. 8.
Effect of Arg1 ablation in the lung on the correlation of lung function, abundance of pulmonary mRNAs and proteins, pulmonary histopathology, and concentrations of plasma amino acids in female mice. The triangle on the upper right side refers to data from Arg1-Con mice and the triangle on the lower left to data from Arg1-KOTie2 mice. The correlation coefficients between the parameters named above the columns and left to the rows, respectively, as measured in all 15 or 16 PBS/OVA- and OVA/OVA-treated mice of the Arg1-Con or Arg1-KOTie2 groups are shown. The significance of the correlations is color-coded: yellow: 0.05 > P > 0.01, orange: 0.01 > P > 0.001, and red: P < 0.001. The near-absence of cross-correlations of parameters between the categories named in the title and the decline of the number or degree of significant correlations in Arg1-KOTie2 compared to Arg1-Con mice is noteworthy