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. 2017 Nov 28;15:241. doi: 10.1186/s12967-017-1347-9

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Expression of angiogenesis-related genes. Normalized expression (2^−ΔCT) of angiogenesis-related genes that are more than fivefold higher expressed in the A-07 and D-12 models than in the R-18 and U-25 models (a), and more than fivefold higher expressed in the R-18 and U-25 models than in the A-07 and D-12 models (b). Gene expression was measured with quantitative PCR and normalized to housekeeping genes with stable expression (GAPDH and ACTB)