Table 1.
Describe baseline characteristics of subjects
| Diabetic group | Non-diabetic group | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Total | Non-RAAS | RAAS1 | RAAS2 | P-value | total | Non-RAAS | RAAS1 | RAAS2 | P-value |
| Sample Size | 15,032 | 10,560 | 623 | 3849 | 17,074 | 14,587 | 588 | 1899 | ||
| Age | 61.0 (11.0) | 61.0 (11.2) | 63.2 (10.9) | 60.6 (10.6) | <0.001 | 65.7 (13.9) | 65.5 (14.3) | 68.2 (11.4) | 66.4 (10.8) | <0.001 |
| Male | 4048 (27) | 2671 (25) | 220 (35) | 1157 (30) | <0.001 | 7659 (45) | 6541 (45) | 269 (46) | 849 (45) | 0.901 |
| BMI | 23.7 (4.0) | 23.4 (4.0) | 23.4 (3.9) | 24.5 (4.0) | <0.001 | 21.8 (4.3) | 21.5 (4.3) | 22.5 (4.1) | 23.2 (4.4) | <0.001 |
| SBP | 128.0 (20.2) | 124.0 (19.8) | 127.7 (20.6) | 131.1 (19.7) | <0.001 | 127.8 (23.9) | 124.4 (23.1) | 135.1 (23.8) | 137.3 (23.5) | <0.001 |
| DBP | 77.4 (11.4) | 75.7 (11.3) | 77.3 (11.3) | 78.8 (11.4) | <0.001 | 77.4 (17.4) | 75.9 (18.5) | 80.3 (13.6) | 81.6 (13.4) | <0.001 |
| Comorbidity | ||||||||||
| Hypertension | 7059 (47) | 3632 (34) | 480 (77) | 2947 (77) | <0.001 | 6742 (39) | 4466 (31) | 510 (87) | 1766 (93) | <0.001 |
| CVD | 1712 (11) | 1129 (11) | 98 (16) | 485 (13) | <0.001 | 2659 (16) | 2108 (14) | 122 (21) | 429 (23) | <0.001 |
| HDL | 37.7 (11.0) | 37.4 (10.8) | 37.3 (10.5) | 38.5 (11.5) | <0.001 | 40.2 (9.0) | 40.0 (8.6) | 40.8 (10.7) | 41.6 (11.2) | <0.001 |
| LDL | 115.3 (40.5) | 114.6 (39.9) | 114.8 (40.0) | 117.3 (42.1) | 0.002 | 115.2 (32.8) | 114.2 (31.2) | 119.7 (39.3) | 121.0 (41.2) | <0.001 |
| Albumin | ||||||||||
| A1 | 8657 (58) | 5975 (57) | 383 (61) | 2299 (60) | <0.001 | 11,079 (65) | 9133 (63) | 432 (73) | 1514 (80) | <0.001 |
| A2 | 3367 (22) | 2499 (24) | 100 (16) | 768 (20) | <0.001 | 3485 (20) | 3188 (22) | 77 (13) | 220 (12) | <0.001 |
| A3 | 3008 (20) | 2086 (20) | 140 (22) | 782 (20) | <0.001 | 2510 (15) | 2266 (16) | 79 (13) | 165 (9) | <0.001 |
| GFR | 48.0 (19.0) | 47.1 (19.4) | 42.7 (18.3) | 51.2 (17.6) | <0.001 | 46.0 (22.5) | 45.9 (23.5) | 41.4 (16.5) | 47.9 (14.2) | <0.001 |
| FU time* | 4.7(0.3–13.2) | 4.9 (0.3–14.2) | 2.6 (0.3–11.9) | 4.5 (1.0–13.9) | <0.001 | 4.2(0.3,14.3) | 4.3(0.2–4.3) | 3.0(0.3–3.7) | 4.2(1.0–13.3) | <0.001 |
Values are expressed as mean (SD) for continuous data, except *median (range), number (%) for dichotomous data
RAAS Renin-angiotensin aldosterone system, RASS 1 & 2 Duration = 0.25–1 & > 1 year, CVD Cardiovascular diseases