Table 2.
Table showing semi quantitatively the magnitude of expressions for TNFR1 and TNFR2 immunoreactions (IR)
| Animals showing normal morphology TNF Receptor type 1 | Animals showing normal morphology TNF Receptor type 2 | Animals expressing myositis TNF Receptor type 1 | Animals showing myositis TNF Receptor type 2 | |
|---|---|---|---|---|
| Abnormal muscle fibers | - | - | ++ | - |
| Necrotic muscle fibers with invading cells | - | - | - | ++ |
| Muscle nuclei | - | +++ | - | +++ |
| White blood cells | - | - | + | +++ |
| NMJ | - | +++ | - | +++ |
| Nerve fascicles | (+) | (+) | ++ | ++ |
– (no reaction), (+) (very limited reaction, + (moderate reaction), ++ (marked reaction), +++ (very marked/regularly occurring reaction). The animals for which a clear myositis was seen (related to most animals from groups 4 and 6 and sometimes those from group 5) and for which a normal muscle morphology occurred (related to animals from groups 1–3 and occasional animals from group 5)