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. 2017 Nov 28;18:526. doi: 10.1186/s12859-017-1928-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 15 — Surface cell-scaffold contact (d) derived from the original scaffold z-stack (a) after applying modified Frangi’s vessel enhancement filtering (b) and verified cell mask (c). The results correspond to the method A6 and medium microfiber scaffold type (illustration shows one frame of a z-stack)