Table 2.
Outcomes of RAS testing in Round 3 of the physician survey study
| Outcome | No. of oncologists (%) (95% CI) |
|---|---|
| All oncologists | (N = 152) |
| Aware RAS testing should be performed prior to initiation of panitumumab | 152 (100.0) (100.0–100.0) |
| Aware of the correct indication for panitumumab for treatment of patients with mCRC and wild-type RAS tumoursa | 145 (95.4) (92.1–98.7) |
| Aware of patients’ tumour RAS status prior to initiation of panitumumab treatment in the past 6 months of routine clinical practiceb | 143 (94.1) (90.3–97.8) |
| Administered panitumumab to only patients with mCRC and wild-type RAS in the past 6 months of routine clinical practicec | 131 (86.2) (80.7–91.7) |
| Subset of oncologists who administered panitumumab concurrently with oxaliplatin-containing chemotherapy | (N = 105) |
| Administered panitumumab with concurrent oxaliplatin-containing chemotherapy to only patients with mCRC and wild-type RAS in the past 6 months of routine clinical practiced | 97 (92.4) (87.3–97.5) |
CI confidence interval, mCRC metastatic colorectal cancer
aSix oncologists responded for treatment of patients with mutant RAS tumours and one oncologist gave a ‘not sure’ response
bEight oncologists were unaware of patients’ tumour RAS status before initiation of panitumumab treatment and one oncologist gave a ‘not sure’ response
cNineteen oncologists had administered panitumumab to patients with mCRC and mutant RAS tumours or with unknown tumour RAS status, and two oncologists gave a ‘not sure’ response
dEight oncologists had administered panitumumab with concurrent oxaliplatin-containing chemotherapy to patients with mCRC and mutant RAS tumours or with tumour RAS status unknown