FIGURE 5.

Aromatic L-amino acid decarboxylase cells in the white matter expressed oligodendrocyte and radial glial phenotypes but not astroglial or microglial phenotypes. (A1–A3) AADC was not expressed in astrocytes immunolabeled with GFAP (arrows). (B1–B3) AADC was not expressed in microglia immunolabeled with Iba1 (arrows). (C1–C3) AADC was expressed in a small proportion of oligodendrocytes immunolabeled with APC (arrows). Note that only the larger, but not the smaller, APC immunopositive cells (arrowheads) were double-labeled with AADC. (D1–D3) AADC was expressed in radial glial cells immunolabeled with BLBP (arrows). Still not all BLBP-immunolabeled cells were AADC-IR (e.g., marked by an arrowhead). AADC antibody was from rabbit for (A1–C3), from sheep for (D1–D3). All the images were from transverse sections of thoracic (T) segments. Scale bar in (D3), valid for all panels, 100 μm.