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. 2017 Jul 20;21(12):3641–3657. doi: 10.1111/jcmm.13275

Figure 5.

Figure 5

Effects of UCHL1 on the rates of cell survival and death of cultured cortical neurons after 1‐hr OGD/24‐hr R. Quantitative results showed the effects of different doses of LDN on the rate of cell survival (A) and the rate of cell death (B) induced by OGD treatment (n = 6 per group). (C) Representative results of Western blot showed UCHL1 shRNA2 and shRNA3 could obviously decrease UCHL1 protein expression, especially. (D) Quantitative analysis showed the effects of UCHL1 shRNA2 and shRNA3 treatments on the rate of cell death from Normoxia and OGD groups of cPKCγ+/+ and cPKCγ−/− cortical neurons (n = 6 per group), respectively. &&& P < 0.001 versus vehicle of LDN group with the same treatment; ***P < 0.001 versus Normoxia of cPKCγ+/+ neurons; ### P < 0.001 versus corresponding cPKCγ+/+ cortical neurons with the same treatment; +++ P < 0.001 versus NC with the same treatment.