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. 2017 Jun 19;21(12):3298–3308. doi: 10.1111/jcmm.13233

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© 2017 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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STAMP2 gene overexpression suppresses angiogenesis density in WAT and BAT of ApoE^−/−/LDLR ^−/− mice. (A) Immunohistochemical staining (endomucin as angiogenesis marker) showing angiogenesis in adipose tissue (brown staining considered positive staining; scale bar: 20 μm); (B) Semiquantification of endomucin immunohistochemical staining. (C) Immunohistochemical staining (CD31 as angiogenesis marker) showing angiogenesis in adipose tissue (brown staining considered positive staining; scale bar: 20μm); (D) Semiquantification of CD31 immunohistochemical staining. Data are mean ± SD (n = 6 per group). *P < 0.05 versus control + vehicle; ^# P < 0.05 versus DM + vehicle. EWAT, epididymal white adipose tissue; SWAT, subcutaneous white adipose tissue; BAT, brown adipose tissue.