Table 3.
Distribution of clinical and pathologic variables by grade of steatosis. Results are in median (interquartile range) unless otherwise specified.
| N = 593 | Grade 0 N=159 |
Grade 1 N=283 |
Grade 2 N=82 |
Grade 3 N=69 |
P value for trend |
|---|---|---|---|---|---|
| Age, year | 53 (49–58) | 55 (51–59) | 54 (50–58) | 53 (50–56) | 0.6 |
| Female, no (%) | 46 (29%) | 103 (36%) | 35 (43%) | 28 (41%) | 0.032 |
| Weight, pound | 180 (160–205) | 180 (160–203) | 171 (150–205) | 170 (150–213) | 0.3 |
| BMI, kg/m2 | 28 (25–32) | 27 (25–32) | 27 (23–31) | 27 (23–32) | 0.1 |
| Inflammation grade | 2 (1–2) | 2 (1–2) | 2 (2–3) | 2 (1–3) | <0.001 |
| Iron grade | 2 (1–3) | 2 (1–3) | 2 (1–4) | 1 (1–4) | 0.7 |
| Iron in hepatocyte, no (%) | 79 (54%) | 140 (53%) | 31 (39%) | 28 (42%) | 0.022 |
| HBV, no (%) | 5 (3%) | 12 (4%) | 3 (4%) | 3 (4%) | 0.7 |
| HIV, no (%) | 21 (13%) | 26 (9%) | 11 (13%) | 8 (12%) | 0.9 |
| CHF, no (%) | 4 (3%) | 9 (3%) | 3 (4%) | 0 | 0.5 |
| HTN, no (%) | 22 (14%) | 42 (15%) | 16 (20%) | 12 (17%) | 0.3 |
| ESRD, no (%) | 7 (4%) | 9 (3%) | 1 (1%) | 1 (1%) | 0.1 |
| DM, no (%) | 40 (25%) | 56 (20%) | 18 (22%) | 14 (20%) | 0.4 |