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. 2017 Jun 29;21(12):3481–3493. doi: 10.1111/jcmm.13258

Figure 5.

Figure 5

Overexpression or knockdown of eIF4E expression positively regulated EMT, migration and invasion of gastric cancer cells in parallel with regulation of MMP‐9 and Twist expression. A, B and C, SGC7901 and MGC803 cells were transiently transfected with eIF4E overexpression constructs or the control vector for 48 hrs, then subjected to Western blot (A), migration (B) and invasion (C) assays. (D, E and F), these two cell lines were transiently transfected with eIF4E siRNA or control siRNA for 24 hrs and then subjected to Western blot (D), migration (E) and invasion (F) assays. Magnification, 100×. Columns, means of five fields; bars, S.D. *P < 0.05. The data are representatives of three independent experiments.