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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Epilepsy Res. 2017 Aug 24;137:139–144. doi: 10.1016/j.eplepsyres.2017.08.005

Fig. 4. Atomoxetine produces no effect on the heart rate and blood pressures in conscious DBA/1 mice.

Fig. 4

A, changes in mean systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and the heart rate prior to and after IP injection of vehicle or atomoxetine in conscious DBA/1 mice. B, comparison of the normalized mean SBP, DBP, MAP and heart rate between vehicle and atomoxetine in behaving DBA/1 mice at the period of 120–130 min (mean value of 10-min recordings) after injection of vehicle/atomoxetine, at which atomoxetine at this dosage is known to reduce S-IRA (Zhang et al., 2017).