Table 3.
Unstandardized parameter estimates (95% confidence intervals) from the best fitting bivariate biometric model from table 2 (model number 5) of depressive symptoms
Parameter | Men | Women | ||||
---|---|---|---|---|---|---|
Estimate | 95% CI | Estimate | 95% CI | |||
Lower | Upper | Lower | Upper | |||
Additive genetic | ||||||
aCIRS | 6.00 | 5.14 | 6.84 | 5.18 | 4.53 | 5.81 |
acommon | 0.28 | 0.22 | 0.32 | 0.26 | 0.18 | 0.32 |
aunique | 3.96 | 3.12 | 4.74 | 5.41 | 4.63 | 6.16 |
βaCIRSc | 0.16 | 0.01 | 0.33 | 0.01 | −0.04 | 0.07 |
βa40u | −0.06 | −0.10 | 0.01 | −0.01 | −0.06 | 0.03 |
βa75u | 0.20 | −0.08 | 0.45 | 0.16 | −0.03 | 0.34 |
βaCIRSu | 0.03 | −0.02 | 0.08 | 0.02 | −0.02 | 0.07 |
Non-shared Environmental | ||||||
eCIRS | 7.90 | 7.35 | 8.46 | 7.12 | 6.69 | 7.55 |
ecommon | 0.14 | 0.10 | 0.17 | 0.15 | 0.12 | 0.19 |
eunique | 6.80 | 6.30 | 7.32 | 7.59 | 7.10 | 8.10 |
βeCIRSc | 0.09 | 0.05 | 0.13 | 0.11 | 0.07 | 0.15 |
βe40u | −0.04 | −0.01 | −0.07 | −0.03 | −0.06 | −0.01 |
βe75u | 0.16 | 0.01 | 0.33 | 0.03 | −0.09 | 0.16 |
βeCIRSu | 0.10 | 0.07 | 0.13 | 0.06 | 0.03 | 0.09 |
Notes: aCIRS represents the additive genetic genetic path estimate to the additive genetic I-CIRS factor at age 75; acommon = the common pathway estimate of the additive genetic contributions of I-CIRS on depressive symptoms; aunique = the estimated variance unique to depressive symptoms at age 75; βaCIRSc = the estimate of the moderating effect of I-CIRS on the additive genetic covariance. βa40u = the estimate of the linear slope on the additive genetic variance unique to depressive symptoms for participants aged 40 to 75; βa75u = the estimate of the linear slope on the additive genetic variance unique to depressive symptoms for participants aged 75 to 90. βaCIRSu = the estimate of the moderating effect of I-CIRS on the additive genetic variance unique to depressive symptoms. The parameters denoted with an e represent corresponding parameter estimates for the non-shared environmental contributions.