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. Author manuscript; available in PMC: 2018 Apr 12.
Published in final edited form as: Nature. 2017 Oct 4;550(7675):280–284. doi: 10.1038/nature24049

Extended Data Fig. 7. Detailed analysis of LwaCas13a and RNAi knockdown variability (standard deviation) across all samples.

Extended Data Fig. 7

a, Heatmap of correlations (Kendall's tau) for log2(transcripts per million (TPM+1)) values of all genes detected in RNA-seq libraries between targeting and non-targeting replicates for shRNA or guide targeting either luciferase reporters or endogenous genes. b, Heatmap of correlations (Kendall's tau) for log2(transcripts per million (TPM+1)) values of all genes detected in RNA-seq libraries between all replicates and perturbations. c,Distributions of standard deviations for log2(transcripts per million (TPM+1)) values of all genes detected in RNA-seq libraries among targeting and non-targeting replicates for each gene targeted for either shRNA or guide.