Figure 7. PRPF8 forms nuclear structures that co-localize with XAB2, which are consistent with interchromatin granules.

Cells were treated with the siRNAs shown, followed by 10 Gy IR and 30 min recovery prior to mild detergent pre-extraction, fixation, and immunofluorescence analysis. Shown are immunofluorescence signals from representative cells (scale bar = 10 μm).