Table 2. Primary tumor sidedness and pathological and genetic characteristics related with deficiency of mismatch repair genes (N = 201).
Primary tumor sidedness | P-value | ||
---|---|---|---|
Variable | Right (n = 56) | Left (n = 145) | |
Medullary type | |||
Yes | 52 | 144 | 0.022 |
No | 4 | 1 | |
Mucinous type | |||
Yes | 47 | 139 | 0.007 |
No | 9 | 6 | |
Signet ring type | |||
Yes | 55 | 143 | 0.999 |
No | 1 | 2 | |
Tumor infiltrating lymphocytesa | |||
Yes | 13 | 23 | 0.223 |
No | 43 | 122 | |
MLH1/MSH2 status | |||
Normal | 22 | 69 | 0.013 |
Abnormal | 10 | 9 | |
Hypermutated phenotype | |||
Hypermutated | 10 | 7 | 0.008 |
Non-hypermutated | 46 | 138 |
a Cut-off value = 10 lymphocytes/5 high power fields.