Table 2. The hazard ratios of Heng risk factor for PFS and OS in SM/MM patients stratified by TFI.
HR (95% CI) | p-value | |||
---|---|---|---|---|
Total set | Synchronous | PFS | 1.82 (1.38-2.39) | <.001 |
OS | 2.25 (1.67-3.04) | <.001 | ||
Metachronous | PFS | 0.96 (0.52-1.78) | 0.999 | |
OS | 1.13 (0.57-2.24) | 0.754 | ||
TFI < 1 year set | Synchronous | PFS | 1.81 (1.37-2.38) | <.001 |
OS | 2.19 (1.63-2.94) | <.001 | ||
Metachronous | PFS | 1.6 (0.58-4.43) | 0.385 | |
OS | 2 (0.65-6.19) | 0.159 | ||
TFI ≥ 1 year set | Synchronous | PFS | N.A. | N.A |
OS | N.A. | N.A | ||
Metachronous | PFS | 0.93 (0.43-2.02) | 0.928 | |
OS | 1 (0.42-2.41) | 0.905 |
HR; hazard ratio, CI; confidence interval, TFI; treatment-free interval, PFS; progression-free survival, OS; overall survival; N.A, not available due to small number of patients in SM group with TFI ≥ 1 year set.