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. 2017 Sep 6;8(55):93633–93643. doi: 10.18632/oncotarget.20674

Table 2. The hazard ratios of Heng risk factor for PFS and OS in SM/MM patients stratified by TFI.

HR (95% CI) p-value
Total set Synchronous PFS 1.82 (1.38-2.39) <.001
OS 2.25 (1.67-3.04) <.001
Metachronous PFS 0.96 (0.52-1.78) 0.999
OS 1.13 (0.57-2.24) 0.754
TFI < 1 year set Synchronous PFS 1.81 (1.37-2.38) <.001
OS 2.19 (1.63-2.94) <.001
Metachronous PFS 1.6 (0.58-4.43) 0.385
OS 2 (0.65-6.19) 0.159
TFI ≥ 1 year set Synchronous PFS N.A. N.A
OS N.A. N.A
Metachronous PFS 0.93 (0.43-2.02) 0.928
OS 1 (0.42-2.41) 0.905

HR; hazard ratio, CI; confidence interval, TFI; treatment-free interval, PFS; progression-free survival, OS; overall survival; N.A, not available due to small number of patients in SM group with TFI ≥ 1 year set.