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. 2017 Sep 27;8(55):93924–93941. doi: 10.18632/oncotarget.21370

Figure 4. Klf4 suppressed tumor growth of NPC cells in nude mice.

Figure 4

As mentioned in Materials and methods section, nude mice were subcutaneously implanted with vector- and Klf4-expressing HONE1 cells (A,C,E,G,H) or shSCR- and shKlf4-expressing HONE1 cells (B,D,F,G,H). (A-B) Growth curve of tumor volumes. (C-D) Representative picture of tumors formed. (E-F) Tumors were weighted. (G-H) BrdU, Ki67 and p21-stained sections of transplanted tumors formed by HONE1 cells. The percentages of BrdU-, Ki67- or p21-positive cancer cells were calculated by the total number of BrdU-, Ki67- or p21-positive cells over total number of cancer cells.