Table 2. The viability of GC cells in which DUSP4 was knocked down or overexpressed treated with different concentrations of DOX.
cell lines | IC50(μg/ml) | ||
---|---|---|---|
Negative+ DOX | DUSP4 siRNA+ DOX | DUSP4 plasmid+DOX | |
SGC7901 | 0.831(0.7142 to 0.9478) | 0.4135(0.3733 to 0.4538) | 1.734(0.9695 to 2.498) |
BGC | 1.039(0.9223 to 1.155) | 0.7258(0.6675 to 0.7841) | 2.426(1.624 to 3.228) |
KATO | 2.755(2.262 to 3.247) | 0.4289(0.4031 to 0.4547) | 3.718(2.742 to 4.694) |
mkn45 | 3.198(2.536 to 3.860) | 0.4323(0.3490 to 0.5155) | 5.127(2.440 to 7.814) |
IC50 values show Doxorubicin concentration [μg/ml. mean (95% confidence intervals)].