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. 2017 Oct 10;8(55):94358–94370. doi: 10.18632/oncotarget.21719

Figure 2. Influence of lncRNA XIST on the malignant phenotypes of prostate cancer in vitro.

Figure 2

(A, B) Relative expression of XIST in DU145 or LNCAP cells after transfection with XIST or si-XIST. **P<0.01 vs. NC group or si-NC group. (C, D) CCK-8 assays were performed to determine cellular proliferation in DU145 cells transfected with XIST and LNCAP cells transfected with si-XIST. *P<0.05 vs. NC group or si-NC group. (E, G) Cell cycle of DU145 cells transfected with XIST or NC was detected by flow cytometry. *P<0.05 vs. NC group. (F, H) Cell cycle of LNCAP cells transfected with si-XIST or si-NC was examined by flow cytometry. *P<0.05 vs. si-NC group. (I, J) Wound healing assays were performed to evaluate cell migratory ability in DU145 cells transfected with XIST or NC and LNCAP cells transfected with si-XIST or si-NC. (K-M) Transwell invasion assays were performed to examine invasive ability in cells. Cell number was counted in five random fields at 200 × magnification. *P<0.05 vs. NC group or si-NC group. Data are presented as mean ± SD from three separated experiments.