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. 2017 Oct 10;8(55):94358–94370. doi: 10.18632/oncotarget.21719

Figure 3. MiR-23a is inversely correlated with the expression of XIST.

Figure 3

(A) MiR-23a expression in prostate cancer cell lines (PC3, DU145 and LNCAP) and human prostate epithelial cell line RWPE1 was examined by qRT-PCR. *P<0.05 vs. RWPE1 group. (B) miR-23a expression was negatively correlated with metastasis in prostate cancer. *P<0.05 vs. Normal group. (C) Pearson’s correlation analysis was performed to determine the relationship between miR-23a and lncRNA XIST. (D) The expression level of miR-23a in DU145 and LNCAP cells transfected with miR-23a mimics and miR-23a inhibitors was measured by qRT-PCR. *P<0.05 vs. respective control group. (E) Relative expression of XIST in DU145 and LNCAP transfected with miR-23a mimics and miR-23a inhibitors was determined by qRT-PCR. (F) Relative expression of miR-23a in DU145 and LNCAP cells transfected with XIST and si-XIST was examined by qRT-PCR. *P<0.05 vs. respective control group. Data are presented as mean ± SD in three independent experiments.