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. 2017 Oct 10;8(55):94358–94370. doi: 10.18632/oncotarget.21719

Figure 6. LncRNA XIST suppresses tumor growth of prostate cancer in vivo.

Figure 6

(A) Photographs of tumors excised from nude mice derived 28 days after subcutaneous inoculation of DU145 cells transfected with XIST or NC. (B) The expression of Ki-67 and RKIP in xenograft samples were assessed by Immunohistochemical staining. Analyses of relative average integrated optical density (IOD) using Image Pro-Plus software. (C) Tumor volumes were calculated every 5 days from day 5 to day 28 after inoculation. Bars indicate SD. (D) Tumor weight of xenograft tumors were measured and analyzed. *P<0.05 vs. NC group. (E) Qrt-PCR was performed to determine the expression of XIST in xenografts. *P<0.05 vs. NC group. Data are presented as mean ± SD in three independent experiments.